Immunoglobulins (Igs) have received increasing attention with the powerful function to elicit humoral immunity, kill the invading microbes such as bacteria, chemical substances, viruses, and parasites, and prevent infections from spreading to other regions of the body. Among all types of Igs, IgG is the most abundant isotype found in human serum and the most well-studied one. However, other non-IgG isotypes (IgM, IgA, IgE, etc.) also play important roles in a variety of applications, especially in diagnosis research.
Creative Biolabs is for years fully focused on the extensive and complete portfolio of laboratory and manufacturing services and products for antibody research, and has gathered a team of scientists focusing on non-IgG antibodies. The list of non-IgG-related products has been constantly updated to benefit diagnosis research.
- IgA Products and Diagnostic Applications of IgA Antibodies
IgA is the second most abundant antibody in human serum, playing an important role in the primary defense against infections. Research has shown its function in diagnosis of tuberculosis and latent tuberculosis infection, and Cystoisospora suis infections.
Creative Biolabs provides a number of premade IgA monoclonal and polyclonal antibodies with a high level of purity. Customers can choose from products of different hosts (mouse, goat, rabbit, human immunodeficiency virus, etc.), species reactivities (astrovirus, rotavirus A, human, rat, mouse, hepatitic virus, etc.), as well as applications (WB, IHC, ELISA, IF, FC, etc.).
- IgM Products and Diagnostic Applications of IgM Antibodies
IgM, the largest antibody, is the first antibody to appear in response to initial exposure to an antigen. IgM detections have been proved to be useful for the diagnosis of congenital infections such as Toxoplasmosis, syphilis, rubella, cytomegalovirus infection, and human immunodeficiency viruses (HIV) infection.
Being devoted to providing a comprehensive range of in vitro diagnostic (IVD) antibody products and services, Creative Biolabs specializes in creating and producing high-quality recombinant IgM antibodies in a variety of forms for applications covering WB, ChIP, IF, IP, FC, etc.
- IgE Products and Diagnostic Applications of IgE Antibodies
IgE’s central function is to provide immune defense against various parasites. Furthermore, it has an essential role in allergic diseases and is found to be elevated in various autoimmune diseases, including aeroallergen inhalation-induced disease, drug allergy, and food allergy.
Creative Biolabs is fully engaged in offering high-quality IgE antibodies for diagnostic applications to customers all over the world. The product list covers the host of mouse, human cell, goat, and the species reactivity of chicken, human, porcine, etc.
The products are for research use only. More information can be found on the official website: https://non-igg-ab.creative-biolabs.com/.
About Creative Biolabs
Empowered by leading technology and years of experience in biomedical science, Creative Biolabs is skilled at providing non-IgG therapeutic antibody development services with the support of the cutting-edge Antibody GlycoOpitimize Platform and Expression System Platform. High-quality off-the-shelf non-IgG products (mainly IgA, IgM, and IgE monoclonal/polyclonal antibodies) and non-IgG antibody ELISA kits are also available for both academic and commercial usage.
Disclaimer: The views, suggestions, and opinions expressed here are the sole responsibility of the experts. No Guardian Talks journalist was involved in the writing and production of this article.